You searched for molecular chaperone

CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis

Avi J. Samelson, Nabeela Ariqat, Justin McKetney, et al.

Selected by Kritika Mehta

The Drosophila anterior-posterior axis is polarized by asymmetric myosin activation

Hélène Doerflinger, Vitaly Zimyanin, Daniel St Johnston

Selected by Giuliana Clemente

An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput screens

Robert Coukos, David Yao, Mateo I. Sanchez, et al.

Selected by Lorenzo Lafranchi

Cytosolic aggregation of mitochondrial proteins disrupts cellular homeostasis by stimulating other proteins aggregation

Urszula Nowicka, Piotr Chroscicki, Karen Stroobants, et al.

Selected by Eric McGregor

Selectivity of Protein Interactions along the Aggregation Pathway of α-Synuclein

André D. G. Leitão, Paulina Rudolffi Soto, Alexandre Chappard, et al.

Selected by Utrecht Protein Folding and Assembly

Decoding distinctive features of plasma extracellular vesicles in amyotrophic lateral sclerosis

Laura Pasetto, Stefano Callegaro, Deborah Ferrara, et al.

Selected by Kristina Kuhbandner

Quantitative analysis of the ubiquitin-proteasome system under proteolytic and folding stressors

Jeremy J. Work, Onn Brandmann

Selected by Sandra Malmgren Hill

Skd3 (human CLPB) is a potent mitochondrial protein disaggregase that is inactivated by 3-methylglutaconic aciduria-linked mutations

Ryan R. Cupo, James Shorter

Selected by Tessa Sinnige

Nix induced mitochondrial fission, mitophagy, and myocyte insulin resistance are abrogated by PKA phosphorylation

Simone Cristina da Silva Rosa, Matthew D. Martens, Jared T. Field, et al.

Selected by Sandra Franco Iborra

HSP110 dependent HSP70 disaggregation machinery mediates prion-like propagation of amyloidogenic proteins in metazoa

Jessica Tittelmeier, Carl Alexander Sandhof, Heidrun Maja Ries, et al.

Selected by Tessa Sinnige

Correction of Niemann-Pick type C1 disease with the histone deacetylase inhibitor valproic acid

Kanagaraj Subramanian, Darren M Hutt, Vijay Gupta, et al.

Selected by Joanna Cross

Modulation of neuronal resilience during aging by Hsp70/Hsp90/STI1 chaperone system

Rachel Lackie, Abdul Razzaq, Sali M.K. Farhan, et al.